Quotation Stöllberger, Claudia, Lutz, Wolfgang, Finsterer, Josef . 2009. Heat-related side-effects of neurological and non-neurological medication may increase heatwave fatalities. European Journal of Neurology, 16 (7), 879-882.


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Abstract

Background: During the 2003 French heatwave 15 000 excess deaths were registered. One fifths died from the combination of dehydration, heatstroke, and hyperthermia and one tenth from dehydration, despite abundant water. Methods and Results: We hypothesized that physiologic adaptation to heat was not effective in the victims attributable to side-effects of drugs (impaired thermoregulation, suppressed thirst) many of these patients were taking. This could explain why many victims died of dehydration despite availability of water. As a consequence of the global climate change heatwaves may occur more frequently and may be more intense, with a strong impact on the future selection of drugs in elderly patients. Conclusion: Insufficient water intake, impaired thermoregulation, and resulting death may be directly linked to the use of certain drugs, implying an immediate need for public awareness during heatwaves and for long-term strategies to mitigate the expected increase in future heatwave-related fatalities.

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Publication's profile

Status of publication Published
Affiliation WU
Type of publication Journal article
Journal European Journal of Neurology
Citation Index SCI
Language English
Title Heat-related side-effects of neurological and non-neurological medication may increase heatwave fatalities
Volume 16
Number 7
Year 2009
Page from 879
Page to 882
Reviewed? Y
URL http://www3.interscience.wiley.com/journal/122350148/abstract
DOI http://dx.doi.org/10.1111/j.1468-1331.2009.02581.x
Open Access N

Associations

People
Lutz, Wolfgang (Former researcher)
External
Finsterer, Josef
Stöllberger, Claudia
Organization
Institute for Statistics and Mathematics IN (Details)
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